Prurigo nodularis is the formation of hard, intensely itchy bumps on the skin. Scratching causes the skin to open.
Excessive scratching of an itch causes prurigo nodularis. The initial cause of the itch is not always clear, but it may be nerve problems.
Factors that may increase your risk of prurigo nodularis include:
Skin lumps are small (usually < 2 cm) and hard. The top of the lumps may be dry and peeling, or if it has been scratched, may be open and bleeding.
Scratching makes prurigo nodularis worse. Scratching can also cause damage to the surface of the skin and increase your risk of infection. Over time, there may also be some scarring.
A key sign of a prurigo nodularis lump is intense itching. The itching may be constant or sporadic.
You will be asked about your symptoms and your medical history. The diagnosis is usually made based on the appearance of your skin and your symptoms.
Your bodily fluids and tissues may be tested to check for other conditions. This can be done with:
Treatment may take time and involve different therapies until the right one is found. The goal is to reduce itchiness and prevent scratching.
Prurigo nodularis may be treated with:
If initial treatment does not work, the following options may be tried:
If prurigo nodularis affects quality of life or is treatment is not helpful, counseling may be needed to better manage the condition.
American Academy of Dermatology
Family Doctor—American Academy of Family Physicians
Canadian Dermatology Association
The Eczema Society of Canada
Fostini AC, Girolomoni G, et al. Prurigo nodularis: an update on etiopathogenesis and therapy. J Dermatolog Treat. 2013;24(6):458-462.
Lotti, T, Buggiani, G, Prignano F. Prurigo nodularis and lichen simplex chronicus. Dermatol Ther. 2008 Jan-Feb;21(1):42-6.
Nodular prurigo. DermNet NZ website. Available at: http://dermnetnz.org/dermatitis/prurigo-nodularis.html. Updated September 2014. Accessed August 18, 2017.
Prurigo nodularis. American Osteopathic College of Dermatology website. Available at: http://www.aocd.org/?page=prurigonodularis. Accessed August 18, 2017.
Prurigo nodularis Patient.co.uk website. Available at: http://www.patient.co.uk/doctor/Prurigo-Nodularis.htm. Updated January 28, 2016. Accessed August 18, 2017.
Last reviewed September 2017 by EBSCO Medical Review Board Michael Woods, MD FAAP
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.