People with metabolic syndrome are at increased risk of:
Metabolic syndrome is believed to be due to a combination of:
The more risk factors you have for metabolic syndrome, the greater your likelihood of developing it. The risk of having metabolic syndrome also increases with age. If you have a number of risk factors, ask your doctor what you can do to reduce your risk.
Examples of these risk factors include:
About metabolic syndrome. American Heart Association website. Available at: http://www.heart.org/HEARTORG/Conditions/More/MetabolicSyndrome/About-Metabolic-Syndrome_UCM_301920_Article.jsp#.V1bYV02FMdU. Updated August 16, 2012. Accessed May 10, 2013.
Deen D. Metabolic Syndrome: time for action. Am Fam Physician. 2004;69(12):2875-2882.
Ford ES, Giles WH, Dietz WH, et al. Prevalence of the metabolic syndrome among US adults: findings from the Third National Health and Nutrition Examination Survey. JAMA. 2002;287(3):356-359.
Gami AS, Witt BJ, Howard DE, et al. Metabolic syndrome and risk of incident cardiovascular events and death: a systematic review and meta-analysis of longitudinal studies. J Am Coll Cardiol. 2007;49(4):403-414.
Grundy SM. Metabolic syndrome: a multiplex cardiovascular risk factor. J Clin Endocrinol Metab. 2007;92(2):399-404.
Grundy SM, Cleeman JI, Daniels SR, et al. Diagnosis and management of the metabolic syndrome. Circulation. 2005;112(17):2735-2752.
Metabolic syndrome in adults. EBSCO DynaMed Plus website. Available at: http://www.dynamed.com/topics/dmp~AN~T113812/Metabolic-syndrome-in-adults. Updated March 11, 2016. Accessed September 23, 2016.
Weiss R. Dziura J, Burgert Ts, et al. Obesity and the metabolic syndrome in children and adolescents. N Engl J Med. 2004;350(23):2362-2374.
Who is at risk for metabolic syndrome? National Heart, Lung, and Blood Institute website. Available at: http://www.nhlbi.nih.gov/health/health-topics/topics/ms/atrisk. Updated November 6, 2015. Accessed June 7, 2016.
1/2/2014 DynaMed Plus Systematic Literature Surveillance http://www.dynamed.com/topics/dmp~AN~T113812/Metabolic-syndrome-in-adults: Koyama S, Ichikawa G, Kojima M, Shimura N, Sairenchi T, Arisaka O. Adiposity rebound and the development of metabolic syndrome. Pediatrics. 2014;133(1):e114-e119..
1/22/2015 DynaMed Plus Systematic Literature Surveillance http://www.dynamed.com/topics/dmp~AN~T113812/Metabolic-syndrome-in-adults: Xu Y, Shen S, Sun L, Yang H, Jin B, Cao X. Metabolic syndrome risk after gestational diabetes: a systematic review and meta-analysis. PLoS One. 2014;9(1):e87863.
Last reviewed June 2016 by James Cornell, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.