Lymphomas are cancers of the lymphatic system. This system drains excess fluid from the tissue. It also helps protect against infections. Non-Hodgkin lymphoma is a general name that applies to many types of lymphomas, which are based on:
In general, there are 2 main groups:
These cancers are different from Hodgkin lymphoma. This is another type of cancer that affects the lymphatic system.
Some risk factors include:
Symptoms may vary greatly in each child. Symptoms may include:
You will be asked about your child’s symptoms and medical history. A physical exam will be done. It will include an exam of the lymph nodes.
Your child's bodily fluids and tissues may be tested. This can be done with:
Your child's body structures may need to be viewed. This can be done with:
Treatment depends on the stage of the cancer and its type. Talk with the doctor and the healthcare team about the best plan for your child. Treatment options include:
Chemotherapy involves the use of drugs to kill cancer cells. The drugs enter the bloodstream, then travel through the body killing mostly cancer cells. With radiation therapy, radiation is directed at the tumor to kill the cancer cells.
Your child may have a transplant procedure, such as:
These medications are designed after the body's natural cancer-fighting mechanisms. They increase or restore the body’s natural defenses against cancer. One type of biological therapy, interferons, interferes with the division of cancer cells and can slow tumor growth.
Sometimes a drug or antibody that is directed at the lymphoma is linked to a radioactive substance. It will deliver a focused dose of radiation to the tumor.
American Cancer Society
Leukemia and Lymphoma Society
Canadian Cancer Society
Lymphoma Foundation Canada
Non-Hodgkin’s lymphoma in children. American Cancer Society website. Available at: http://www.cancer.org/Cancer/Non-HodgkinLymphomainChildren/DetailedGuide/non-hodgkin-lymphoma-in-children-non-hodgkin-lymphomain-children. Updated March 7, 2014. Accessed March 10, 2016.
Non-Hodgkin’s lymphoma. Children’s Hospital of Wisconsin website. Available at: http://www.chw.org/display/PPF/DocID/21526/router.asp. Accessed March 10, 2016.
Non-Hodgkin lymphoma (HL). EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated February 25, 2016. Accessed March 10, 2016.
2/5/2013 DynaMed's Systematic Literature Surveillance http://www.ebscohost.com/dynamed: Kharazmi E, Fallah M, Sundquist K, et al. Familial risk of early and late onset cancer: nationwide prospective cohort study. BMJ. 2012;345:e8076.
Last reviewed March 2016 by Kari Kassir, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.